Transcriptomics,Genomics

Dataset Information

153

Genome wide gene expression profiling demonstrated that mouse ESC and iPSC differentiated osteoblast progenitors resemble osteoblasts


ABSTRACT: We differentiated mouse Col2.3 GFP ESCs and iPSCs to osteoblast progenitors and confirmed the osteoblast identity of ESC- and iPSC-derived osteoblasts using RNA-sequencing and hierarchical clustering, and demonstrate that Col2.3GFP+ sorted cells are more similar to freshly isolated Col2.3GFP+ osteoblasts from mouse bone than to unsorted cells based on whole genome expression profiling. Overall design: ESC- and iPSC-derived osteoblasts, and Col2.3GFP+ sorted cells and freshly isolated Col2.3GFP+ osteoblasts

INSTRUMENT(S): Illumina HiSeq 2500 (Mus musculus)

SUBMITTER: Hui Zhu  

PROVIDER: GSE110434 | GEO | 2018-05-01

REPOSITORIES: GEO

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