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Genome-wide maps of Trim33, Ctcf and H3K27ac binding in embryoid bodies

ABSTRACT: We report high throughput profiling and co-occupancy of Trim33, Ctcf and H3K27ac in differentiating embryoid bodies derived from mouse embryonic stem cells. An average of ~37 million reads were generated for each of the described samples and input sample generating 4,426, 52,446, 30,047 peaks respectively for Trim33, CTCF and H3K27ac. Motif enrichment analyses for Trim33 ChiP-Seq data returned CTCF and BORIS (CTCF analog) motifs as best matches. Of the merged peaks, 723 were shared by Trim33, CTCF as well as H3K27ac. In addition, 1299 peaks were shared by Trim33 and CTCF, 1131 were shared by Trim33 and H3K27ac and 3321 were shared by CTCF and H3K27ac.

ORGANISM(S): Mus musculus

PROVIDER: GSE119874 | GEO | 2019/01/01

REPOSITORIES: GEO

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Trim33 binds and silences a class of young endogenous retroviruses in the mouse testis

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