Project description:Analyzing UHRF2 targets in macrophages during VSV infection Cleavage under targets and tagmentation (CUT&Tag)-seq for regulator of IFN-I in primary mouse macrophages during VSV infection
Project description:To investigate the function PFKFB3 in RNA virus infection, we established PFKFB3 overexpressed A549 cell lines and infected cells with VSV.
Project description:Wild type or HIPK2-/- immortalized bone marrow-derived macrophages (iBMDM) were infected with VSV for 6h, followed by whole genome RNA-seq analysis. Conclusions: HIPK2 deficiency aggravates viral infection and inhibited the production of IFNβ.
