Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Interferon-beta-inducible genes in human monocyte-derived macrophages (MDMs)

ABSTRACT: Transcriptome analysis of human macrophages stimulated with Interferon Beta at different time points. Control Media data for all different time points can be found at Series GSE82227.

ORGANISM(S): Homo sapiens

PROVIDER: GSE125352 | GEO | 2019/01/19

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Interferon-beta-inducible genes in human monocyte-derived macrophages (MDMs)

Project description:Interferon-beta-inducible genes in human monocyte-derived macrophages (MDMs)

| PRJNA515908 | ENA

Profiling of interferon beta immediate transcriptional effects in humans

Project description:In this study we used high frequency sampling and DNA microarrays to analyze the longitudinal transcriptional profile of blood cells taken from two individuals only hours after interferon beta administration and up to a week later as compared to samples taken from healthy controls taken at coordinated time points. Keywords: Time series

2007-04-18 | GSE5678 | GEO

Fibroblast Serum Stimulation Time Course

Project description:Foreskin fibroblasts CRL 2091 (ATCC) were serum starved for 48 hours, and harvested at the indicated time points after switching to media with 10% FBS essentially as described (Iyer et al., 1999). RNA from all of the sampled time points were pooled as reference RNA to compare with RNA from individual time points as described (Iyer et al., 1999). Groups of assays that are related as part of a time series. Keywords: time_series_design

2005-12-31 | GSE3945 | GEO

Time course of PBL derived avian macrophages stimulated with whole Ecoli or LPS

Project description:This series compares gene expression in chicken peripheral blood lymphocyte (PBL) derived macrophages following stimulation with either XL10 E. coli or S. typh LPS over an 8 hour time course (0,1,2,4,and 8 hours). For the late time points, the stimuli were removed after 2 hours and fresh media was added for the remaining time. Keywords: time-course

2004-09-24 | GSE1794 | GEO

TLR2/1 ligand and IFN-g inducible genes in human monocyte-derived macrophages (MDMs)

Project description:Transcriptome profiles for innate and adaptive immune stimuli important for host response against mycobacteria. Human monocyte-derived macrophages were stimulated with TLR2/1 ligand and interferon-g, stimuli present during innate and adaptive immune responses, respectively.

2016-06-08 | GSE82227 | GEO

Transcriptional Response of Human Microglial Cells to Interferon-gamma

Project description:Microglial cells are resident macrophages in the central nervous system (CNS) and play a pivotal role in the innate and adaptive immune responses against microbial infections. The immune functions of microglia are regulated by a milieu of cytokines including interferon (IFN)-gamma. We here performed a series of experiments to acertain the transcriptional profile of human fetal microglial cells at 1, 6, and 24 h after IFN-gamma treatment. Primary human microglial cells were either untreated or treated with 200u/ml IFN-gamma. Affymetrix U133A chips were utilized. Four different tissue samples (B18, O, W, and Y20) were analyzed at the three time points. Keywords = Microglia Keywords = Interferon-gamma Keywords: time-course

2004-12-25 | GSE1432 | GEO

Murine EDMD

Project description:Study muscle regeneration in Emerin and Lamin AC KO mice. Gastrocnemius muscles were injected with cardiotoxin. Muscles were isolated at different time points. Keywords: Time-Series

2006-07-13 | GSE5304 | GEO

Tn-Seq Survival Profiling

Project description:A Tn5 transposon insertion library generated in a thyA- strain was selected in thymidine-free media and insertions were mapped and sequenced at different time points to look for changes in survival caused by gene disruptions

2022-10-11 | GSE147760 | GEO

Analyzing the metabolic stress response of recombinant Escherichia coli cultures expressing human interferon beta in high cell density fed batch cultures using time course transcriptomic data

Project description:Over expression of recombinant proteins is known to cause a metabolic burden to the host cells which leads to down regulation of both growth rates and protein expression. Most studies in this regard have been conducted in low density shake flask cultures which does not capture the essential features of an industrial scale bioprocess. In the present work we studied the transcriptomic profiling at different specific growth rates while expressing the recombinant human interferon beta in fed batch cultures with complex media. These conditions mimicked the industrial fermentations for recombinant proteins. To determine the transcriptomic response of E.coli BL21(DE3) to recombinant protein production at three different specific growth rates, samples were collected for four time points (0h, 2h, 4h, 6h) post induction for the fed batch cultivations at specific growth rates 0.2h-1, 0.3h-1, 0.4h-1 respectively and induced at an optical density of 30. 0h (uninduced) sample was taken as control conditions for every run.

2011-04-06 | E-GEOD-28412 | biostudies-arrayexpress

Proteomic characterization of the culture supernatant of Mycobacterium bovis in different growth stages

Project description:The goal of this study is to identify the different proteins secreted by Mycobacterium bovis in the culture media at different stages of bacterial growth. A field strain of M. bovis was allowed to grow in a culture media and culture supernatant was collected at three-time points representing approximately three different phases of growth. The supernatant was digested by trypsin and analyzed by LC-MS/MS analysis

2021-12-30 | PXD017817 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data