CRISPR screens are feasible in TP53 wild-type cells

ABSTRACT: CRISPR-Cas9 genome-wide screens were performed in retinal pigment epithelial cells (RPE1) with either wild-type TP53 gene, or a TP53-null background. Results show wild-type TP53 has minimal impact on the efficiency of CRISPR dropout screens.

ORGANISM(S): Homo sapiens

PROVIDER: GSE128210 | GEO | 2019/04/30

REPOSITORIES: GEO