Methylation profiling

Dataset Information

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DNA demethylation in CD4-CD8-TCR-ab compared to CD8+ T cells in B6.MRL-FASlpr mice


ABSTRACT: To understand the DNA methylation differences associated with CD4-CD8-TCR-ab (DN) T cells that accumulate in the B6.MRL-FASlpr mouse model we performed reduced representation bisulfite sequencing on these cells compared to CD8+ T cells derived from the lymph nodes. Overall we observed that 95% of the differential CpG were demethylated in DN T cells compared to CD8+ T cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE155293 | GEO | 2020/10/06

REPOSITORIES: GEO

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