Genomics

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Transcriptional analysis of the Neisseria gonorrhoeae Fur regulon


ABSTRACT: In Neisseria gonorrhoeae, Fur (ferric uptake regulator) protein regulates iron homeostasis gene expression through binding to conserved sequences in promoters of iron-responsive genes. We have expanded the gonococcal Fur regulon using a custom microarray to monitor iron-responsive gene expression throughout the growth curve combined with a genome-wide in silico analysis to predict Fur boxes (FB), and in vivo FuRTA assays to detect genes able to bind Fur. Keywords: time course: (1hr ,2hr, 3hr, 4hr)

ORGANISM(S): Neisseria meningitidis Neisseria gonorrhoeae Neisseria gonorrhoeae FA 1090

PROVIDER: GSE16352 | GEO | 2010/01/01

SECONDARY ACCESSION(S): PRJNA115309

REPOSITORIES: GEO

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