Single cell sequence of tumor infiltrated immune cells after cisplatin treatment in control or miR-21 KO in mouse oral cancer model

ABSTRACT: Single cell sequence (SC-seq) has been used to explore the effect of miR-21-modulated chemotherapy-induced tumor microenvironment change. MTC-Q1 WT or MTC-Q1 miR-21 KO cells were subcutaneously injected into C57BL/6 mice. CD45+ immune cells has been isolated after cisplatin injection. The isolated immune cell were sequenced by dropped based scRNA-seq, cDNA were sequenced by Illumina Novaseq 6000.

ORGANISM(S): Mus musculus

PROVIDER: GSE172326 | GEO | 2022/08/29

REPOSITORIES: GEO