Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Caenorhabditis elegans Saccharomyces cerevisiae human feces metagenome Homo sapiens Drosophila melanogaster

PROVIDER: GSE180656 | GEO | 2021/11/18

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling.

Project description: Not available

| S-EPMC8646010 | biostudies-literature

Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling (Nanopore)

Project description:Pseudouridine (Ψ) is an abundant mRNA modification in the mammalian transcriptome, but its function has remained elusive due to the difficulty of transcriptome-wide mapping. We develop nanopore native RNA sequencing for quantitative Ψ analysis that utilizes native content training, machine learning model prediction, and single read coordination. We find interferon inducible Ψ modifications in the interferon stimulated gene transcripts, consistent with a role of Ψ in the efficacy of mRNA vaccines.

2021-11-18 | GSE180654 | GEO

Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling (Illumina)

2021-11-18 | GSE180655 | GEO

Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling (Nanopore)

Project description:Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling (Nanopore)

| PRJNA749032 | ENA

Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling

Project description:Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling

| PRJNA749031 | ENA

Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling (Illumina)

Project description:Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling (Illumina)

| PRJNA749033 | ENA

Sensitive and quantitative probing of pseudouridine modification in mRNA and long noncoding RNA.

Project description: Not available

| S-EPMC6800517 | biostudies-literature

mRNA structure determines modification by pseudouridine synthase 1.

Project description: Not available

| S-EPMC6764900 | biostudies-literature

Simultaneous nanopore profiling of mRNA m6A and pseudouridine reveals translation coordination

Project description:N6-methyladenosine (m6A) and pseudouridine (Ψ) are the two most abundant modifications in mammalian mRNA, but the coordination of their biological functions remains poorly understood. We develop a machine learning-based nanopore direct RNA sequencing method (NanoSPA) that simultaneously analyzes m6A and Ψ in the human transcriptome. Applying NanoSPA to polysome profiling, we reveal opposing transcriptomic co-occurrence of m6A and Ψ and synergistic, hierarchical effects of m6A and Ψ on the polysome.

2024-01-06 | GSE230936 | GEO

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells.

Project description: Not available

| S-EPMC4224642 | biostudies-literature