Dataset Information


Mapping the Burkholderia cenocepacia niche response via high-throughput sequencing

ABSTRACT: Transcriptional profiling of RNA-seq data from two Burkholderia species grown under conditions mimicking the cystic fibrosis lung and the soil environment Overall design: Two condition, two strain experiment. Biological replicates: 2 replicates

INSTRUMENT(S): Illumina Genome Analyzer (Burkholderia cenocepacia)

SUBMITTER: Deborah R. Yoder-Himes 

PROVIDER: GSE19115 | GEO | 2009-11-21



altmetric image


Mapping the Burkholderia cenocepacia niche response via high-throughput sequencing.

Yoder-Himes D R DR   Chain P S G PS   Zhu Y Y   Wurtzel O O   Rubin E M EM   Tiedje James M JM   Sorek R R  

Proceedings of the National Academy of Sciences of the United States of America 20090220 10

Determining how an organism responds to its environment by altering gene expression is key to understanding its ecology. Here, we used RNA-seq to comprehensively and quantitatively assess the transcriptional response of the bacterial opportunistic cystic fibrosis (CF) pathogen and endemic soil dweller, Burkholderia cenocepacia, in conditions mimicking these 2 environments. By sequencing 762 million bases of cDNA from 2 closely related B. cenocepacia strains (one isolated from a CF patient and on  ...[more]

Similar Datasets

2009-12-01 | GSE15817 | GEO
2010-05-19 | E-GEOD-15817 | ArrayExpress
2014-05-30 | E-MTAB-2079 | ArrayExpress
| GSE58353 | GEO
2015-05-05 | PXD001924 | Pride
2012-08-01 | E-MTAB-809 | ArrayExpress
2012-05-11 | E-MEXP-3209 | ArrayExpress
2012-05-10 | E-MEXP-3208 | ArrayExpress
2012-05-11 | E-MEXP-3210 | ArrayExpress
2013-07-15 | E-GEOD-48585 | ArrayExpress