Transcriptomics

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Transcriptome drift of FADU after expression of HIF-1a, Twist1 or Bmi1


ABSTRACT: Expression of HIF-1a or Twist1 or Bmi1 in human hypopharyngeal cancer cell line FADU results in the drift of transcriptome profile from an epithelial cell-like signature to a mesenchymal stem cell-like signature. Overall design: Stable transfection of pHA-HIF1a(dODD), pFLAG-Twist1 or pcDNA3-Bmi1 in FADU cell and analyzed the transcriptome by cDNA microarray. FADU transfected with pcDNA3.1 empty vector was used as a control of experiment.

INSTRUMENT(S): [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

ORGANISM(S): Homo sapiens  

SUBMITTER: Muh-Hwa Yang   

PROVIDER: GSE19406 | GEO | 2010-12-10

SECONDARY ACCESSION(S): PRJNA121777

REPOSITORIES: GEO

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