Transcriptomics

Dataset Information

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Pancreatic stellate and cancer cell transcriptomes from heterocellular, 3D invasive, cultures


ABSTRACT: When combined into spheres and embedded in extracellular matrix, hetero-cellular cultures of pancreatic cancer and stellate cells produce invasive, stellate-led, projections. In order to establish what cancer and stellate cells are expressing in this context we generated chimeric spheres of mouse and human cells. Invasive spheroids could then be processed for RNA sequencing, with reads mapped back to parent species and thus cell type.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE225161 | GEO | 2023/03/22

REPOSITORIES: GEO

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