Genomics

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TopA mutant of P. aeruginosa PA14


ABSTRACT: We have tested the effect of deletion of Topoisomerase I on genes transcription of the bacteria Pseudomonas. aeruginosa. Topoisomerase I is a conserved protein that modulate the topology state of the DNA from super-coiled to relaxed. To this end we have compared the transcription profile of a topA::GentR mutant to that of the wild-type strain. The topA mutant contains in topA gene a Mariner transposon with a gentamicin resistance cassette. It is part of the non-redundant mutant library of P. aeruginosa PA14 strains.

ORGANISM(S): Pseudomonas aeruginosa Pseudomonas aeruginosa PA14

PROVIDER: GSE24038 | GEO | 2011/12/21

SECONDARY ACCESSION(S): PRJNA130337

REPOSITORIES: GEO

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