Genomics

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Transcriptional responses of LPS-stimulated microglia in Alzheimer's disease


ABSTRACT: Neuroimmunity is present as an important mechanism in the brains of Alzheimer's patients, and microglia are a key component of the brain's innate immune response during the development and progression of Alzheimer's disease. The interferon pathway plays an important role in the pathophysiologic mechanisms of AD. RNA-seq was performed on LPS-treated microglia(LPS) and untreated microglia(WT) to further explore.

ORGANISM(S): Mus musculus

PROVIDER: GSE261007 | GEO | 2024/03/11

REPOSITORIES: GEO

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