CUT&RUN analysis of STAT1 and IRF3 in fibroblasts treated with poly(I:C) ± TPCA1
Ontology highlight
ABSTRACT: Analysis of changes in chromatin binding of STAT1 and IRF3 in fibroblast cell line GM02036 (Coriell) after treatment with viral mimetic polyinosinic:polycytidylic acid (poly(I:C)) ± TPCA1.
Project description:Analysis of changes in chromatin binding of RelA in fibroblast cell line GM02036 (Coriell) after treatment with viral mimetic polyinosinic:polycytidylic acid (poly(I:C)) ± TPCA1.
Project description:Analysis of steady-state mRNA levels in human fibroblast GM02036 (Coriell) or retinal pigment epithelium cells after treatment with viral mimetic polyinosinic:polycytidylic acid (poly(I:C)) or double-stranded DNA (dsDNA).
Project description:Analysis of changes in chromatin modifications H3K9me1 and H3K27me3 in fibroblast cell line GM02036 (Coriell) after treatment with TNFa and/or TPCA1.
Project description:Analysis of changes in chromatin modifications H3K37me1 and H3K9me3 in fibroblast cell line GM02036 (Coriell) after treatment with TNFa and/or TPCA1.
Project description:Analysis of changes in chromatin modifications H3K36me3 and H4K20me1 in fibroblast cell line GM02036 (Coriell) after treatment with TNFa and/or TPCA1.
Project description:Analysis of changes in chromatin modifications H3K27ac and H3K4me1 in fibroblast cell line GM02036 (Coriell) after treatment with TNFa and/or TPCA1.
Project description:Analysis of changes in chromatin binding of RelA and MCM2 in fibroblast cell line GM02036 (Coriell) after treatment with TNFa and/or TPCA1.
Project description:Analysis of changes in chromatin modifications H3K27ac and H3K4me1 in fibroblast cell line GM02036 (Coriell) ± heterozygous deletion of 259 bp region on Chr21 (33204248-33204506) after treatment with TNFa.
Project description:Analysis of changes in chromatin binding of RelA and MCM2 in fibroblast cell line GM02036 (Coriell) ± heterozygous deletion of 259 bp region on Chr21 (33204248-33204506) after treatment with TNFa.
Project description:The interferon regulatory factors IRF3 and IRF7 are key players in the regulation of type I and III IFN genes. In this study, we analyzed the role of IRF3 and IRF7 for the host response to influenza A virus infections in Irf3-/-, Irf7-/- and Irf3-/-Irf7-/- knock-out mice.