Transcriptomics

Dataset Information

22

Human airway epithelial responses to rhinovirus infection and cigarette smoke extract alone and in combination


ABSTRACT: This study was performed to test the hypothesis that cigarette smoke extract would alter the responses of primary cultures of human bronchial epithelial cells to infection with purified human rhinovirus 16. The data show marked alterations in rhinovirus-induced expression profiles of a number of genes in the presence of cigarette smoke extract (CSE). Overall design: Cultured epithelial cells from each of 4 donors were exposed to medium alone, rhinovirus 16 (RV16) alone, CSE alone, or RV16 in the presence of CSE. After a 24 h incubation gene expression was assessed.

INSTRUMENT(S): [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

ORGANISM(S): Homo sapiens  

SUBMITTER: David Proud   

PROVIDER: GSE27973 | GEO | 2011-03-15

SECONDARY ACCESSION(S): PRJNA137767

REPOSITORIES: GEO

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