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FUT8 is a critical driver of prostate tumour growth and can be targeted using fucosylation inhibitors

ABSTRACT: To identify signalling pathways altered by FUT8 in prostate cancer cells, we established luciferase-tagged CWR22Rv1 stable cell lines in which FUT8 was overexpressed (OE) and luciferase-tagged PC3 cell lines in which FUT8 was knocked down (KD). We then performed differential gene expression, Gene Ontology and GSEA analyses using data obtained from RNA-seq of the control and FUT8 overexpression, and the control and knockdown cell lines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE280132 | GEO | 2025/05/19

REPOSITORIES: GEO

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