Transcriptomics

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Comparative Transcriptome Analyses Reveal the Responses to Hypoxia Challenge of Mactra veneriformis


ABSTRACT: The transcriptomic analysis of Mactra veneriformis under hypoxia stress was carried out in this paper to explore the response mechanism of M. veneriformis under hypoxia stress from the molecular biological level. The results provided a reference for further study on hypoxia tolerance mechanism and creation of new hypoxia tolerant germplasm of Clams quadricornis. The findings suggest that transcriptome sequencing was performed on M. veneriformis branchial filament tissues under normal and hypoxia conditions by high-throughput sequencing technology, and 54.58Gb of clean data were obtained. There were differences in gene expression between the normal-oxygen group and the hypoxia group. Control group A and hypoxia group B had the most differentially expressed genes (7473 genes), among which 4000 up-regulated genes and 3473 down-regulated genes. Secondly, there were 6407 differentially expressed genes between hypoxia group B and hypoxia group C, with 3535 up-regulated genes and 2872 down-regulated genes. There were 5581 differentially expressed genes in the control group A and the hypoxia group C, 2676 up-regulated genes and 2905 down-regulated genes. According to the enrichment of GO functional annotations, differential genes were mainly concentrated in the membrane of cell components, metabolism in biological processes and binding of molecular functions. The enrichment of KEGG pathway showed that multiple metabolic and genetic information processing pathways were activated.

ORGANISM(S): Mactra quadrangularis

PROVIDER: GSE293462 | GEO | 2025/04/06

REPOSITORIES: GEO

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