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Single cell RNAseq analysis in CT27 human TSC with and without PRMT1 Knockdown

ABSTRACT: The study reports single cell RNA seq analyses of gene expression dynamics in human TSCs. Protein Arginine Methyl Transferase 1 (PRMT1) regulates cellular function via methylation of arginine residues on its target proteins. In this study we depleted PRMT1 in CT27 human TSCs via RNAi. Loss of PRMT1 affects human TSC self-renewal process. We performed single cell RNA-seq with control and PRMT1-knocked down CT27 human TSCs to capture gene expression dynamics at a single cell resolution.

ORGANISM(S): Homo sapiens

PROVIDER: GSE295665 | GEO | 2026/06/15

REPOSITORIES: GEO

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