The role of PurR purine transcriptional repressor and Rae1 endoribonuclease in Erm-mediated macrolide resistance in methicilin-resistant Staphylococcus aureus.

ABSTRACT: Differential gene expression between six S. aureus strains were determined by RNA-seq in 3 biological replicates.The six strains are ermB_minus parental JE2(WT), ermB_proficient strain (KES29), ermB_minus rae1 mutant (MNY205), ermB_proficient rae1 mutant (MNY212), ermB_minus purR mutant (MNY221), and ermB_proficient purR mutant (MNY224). Two culture media were used: A indicates tryptic soy broth (TSB), B indicates RPMI_1640 supplemented with 1% casamino acids.

ORGANISM(S): Staphylococcus aureus

PROVIDER: GSE298918 | GEO | 2026/04/12

REPOSITORIES: GEO