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Analysis of host gene differential expression after PAM cells were infected with ΔD250R ASFV

ABSTRACT: PAMs infected with either WT or ΔD250R ASFV revealed widespread transcriptional upregulation in ΔD250R-infected cells compared with WT-infected cells.The upregulated genes showed significant enrichment of innate immune signaling pathways, with four of the top five pathways corresponding to innate immune activation, including the cytosolic DNA-sensing, NOD-like receptor, RIG-I-like receptor, and Toll-like receptor signaling pathways.

ORGANISM(S): Sus scrofa

PROVIDER: GSE312667 | GEO | 2026/07/22

REPOSITORIES: GEO

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