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Bulk RNAseq of MRGPRX4+/+ and MRGPRX4-/- A2058 human melanoma cells

ABSTRACT: This study investigates the transcriptional consequences of loss of the Mas-related G protein?coupled receptor MRGPRX4 in human melanoma cells. Bulk RNA sequencing was performed on CRISPR-Cas9-engineered MRGPRX4 knockout and control A2058 melanoma cell lines. Sequencing data were processed using established RNA-seq workflows, including quality control and transcript quantification, followed by differential gene expression and functional enrichment analyses to identify gene expression programs regulated by MRGPRX4.

ORGANISM(S): Homo sapiens

PROVIDER: GSE314187 | GEO | 2026/09/15

REPOSITORIES: GEO

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