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Genome-wide DNA methylation analysis of placentas from pregnancies complicated by early-onset fetal growth restriction

ABSTRACT: Fetal growth restriction (FGR) affects approximately 5–10% of pregnancies and remains a leading cause of perinatal morbidity and mortality. The condition is characterized by the failure of the fetus to achieve its genetically determined growth potential, most commonly as a consequence of placental dysfunction. Despite extensive research, the molecular mechanisms underlying FGR remain incompletely understood. In this study, we investigated whether alterations in placental DNA methylation are associated with early-onset FGR and may contribute to its pathophysiology.

ORGANISM(S): Homo sapiens

PROVIDER: GSE314658 | GEO | 2026/02/11

REPOSITORIES: GEO

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