The effects of RBM27 on heart function

ABSTRACT: The goal of this study is to investigate how RBM27 regulates heart function. Total RNA was extracted using Tripure Isolation Reagent (Roche, Mannheim, Germany) from hearts of Rbm27flox/flox and Rbm27-CKO mice at 12 weeks old. Three independent biological replicates for each group were used for RNA-seq. RNA-seq was performed by deep sequencing using an Illumina Novaseq 6000 platform. Paired-end clean reads were aligned to the mouse reference genome(GRCm38/mm10) with Hisat2 v2.0.5, and the aligned reads were used to quantify mRNA expression by using featureCounts v1.5.0-p3.

ORGANISM(S): Mus musculus

PROVIDER: GSE318410 | GEO | 2026/08/18

REPOSITORIES: GEO