SoFIC Orchestrates Physical Barriers and Metabolic Homeostasis to Counter Phage Infection
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ABSTRACT: Bacteria have developed numerous defense systems to counter persistent phage infections. In this study, we characterize the SoFIC defense system, consisting of a Fic family protein. Our results show that SoFIC is widely distributed across multiple bacterial phyla and contains a conserved Fic catalytic motif essential for anti-phage activity.
ORGANISM(S): Escherichia coli
PROVIDER: GSE333263 | GEO | 2026/05/30
REPOSITORIES: GEO
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