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Integrative Transcriptomics Identifies Trazodone as a Modulator of Urban Particulate Matter-Induced Neuroinflammation

ABSTRACT: Urban particulate matter (UPM) triggers neuroinflammation through microglial activation, contributing to the progression of neurodegenerative diseases; however, effective therapeutic interventions remain limited. In this study, we investigated the inhibitory effects of trazodone (TZ), a clinically approved antidepressant, on UPM-induced neuroinflammation using transcriptomic analyses.

ORGANISM(S): Mus musculus

PROVIDER: GSE336648 | GEO | 2026/06/30

REPOSITORIES: GEO

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