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Comparative RNA-seq analysis of PM2.5-induced transcriptional responses in wildtype mouse mammary epithelial cells

ABSTRACT: Fine particulate matter (PM2.5) is an environmental pollutant associated with adverse health effects, including increased cancer risk. To investigate early transcriptional responses to PM2.5 exposure in non-malignant epithelial cells, we performed bulk RNA sequencing of wildtype mouse mammary epithelial EpH4 cells cultured under two-dimensional (2D) conditions. Cells were either left untreated or exposed to PM2.5. This dataset captures genome-wide gene expression changes induced by PM2.5 in wildtype epithelial cells and provides insight into stress response and pathophysiological pathways activated upon particulate matter exposure.

ORGANISM(S): Mus musculus

PROVIDER: GSE336715 | GEO | 2026/07/01

REPOSITORIES: GEO

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