Transcriptomic profiling (RNA-seq) of lung endothelial cells from wild-type (WT) and TET2KO mice following 28 days of Angiotensin II treatment.

ABSTRACT: Chronic hypertension and Angiotensin II infusion induce systemic vascular and endothelial dysfunction. To investigate cell-autonomous transcriptional changes resulting from endothelial-specific TET2 deficiency in the pulmonary microenvironment, we performed total RNA sequencing on lung endothelial cells isolated from wild-type (WT) and endothelial-specific TET2 knockout (TET2KO) mice after 28 days of Angiotensin II treatment.

ORGANISM(S): Mus musculus

PROVIDER: GSE342961 | GEO | 2026/08/10

REPOSITORIES: GEO