Integrated chromatin accessibility and transcriptomic profiling reveals inflammation-associated endothelial remodeling in capillary malformation iECs

ABSTRACT: Integrated bulk ATAC-seq and RNA-seq profiling of induced endothelial cells (iECs) derived from capillary malformation (CM) lesion-derived and control induced pluripotent stem cells (iPSCs). Differential chromatin accessibility, gene expression, transcription factor activity, and candidate peak-to-gene links were analyzed to identify regulatory programs associated with endothelial differentiation and remodeling in CM.

ORGANISM(S): Homo sapiens

PROVIDER: GSE343411 | GEO | 2026/09/30

REPOSITORIES: GEO