KLF2-dependent chromatin accessibility changes in hepatic stellate cells

ABSTRACT: Krüppel-like factor 2 (KLF2) is a transcription factor involved in regulating cellular homeostasis and diverse signaling responses. To investigate KLF2-associated changes in chromatin accessibility in human hepatic stellate cells, we performed ATAC-seq on LX-2 cells stably expressing KLF2 or control vector. Genome-wide chromatin accessibility profiles were compared between the two groups to identify KLF2-dependent changes. This dataset provides a resource for exploring the potential epigenomic mechanisms underlying KLF2-mediated regulation of hepatic stellate cell function.

ORGANISM(S): Homo sapiens

PROVIDER: GSE343805 | GEO | 2026/08/21

REPOSITORIES: GEO