Transcriptome profiling of synovial fibroblasts with ACOX1 overexpression

ABSTRACT: This RNA-seq dataset was generated to investigate the transcriptional changes induced by ACOX1 overexpression in synovial fibroblasts. Synovial fibroblasts were divided into two experimental groups: a control group and an ACOX1-overexpression group. Each group consisted of six biological replicates. Total RNA was extracted from the cells and subjected to transcriptome sequencing. The resulting RNA-seq data were used to characterize ACOX1-associated transcriptional changes, with particular emphasis on inflammatory, metabolic, and extracellular-matrix-related pathways. These data provide transcriptomic evidence for investigating the role of ACOX1 in regulating the functional phenotype of synovial fibroblasts.

ORGANISM(S): Mus musculus

PROVIDER: GSE349121 | GEO | 2026/10/05

REPOSITORIES: GEO