Transcriptomics

Dataset Information

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Expression data from laser capture microdissected human atherosclerotic plaque, rich or void of plasmacytoid dendritic cells


ABSTRACT: Plasmacytoid dendritic cells (pDCs) are scarcely present in the inflamed human atherosclerotic plaque, where they are presumed to exert pro-inflammatory functions through release of type I interferons. However, the precise role of pDCs in human atherosclerosis yet remains to be established. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process.

ORGANISM(S): Homo sapiens

PROVIDER: GSE49670 | GEO | 2013/08/26

SECONDARY ACCESSION(S): PRJNA214692

REPOSITORIES: GEO

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