Ontology highlight
ABSTRACT:
INSTRUMENT(S): NimbleGen Mouse Deluxe Promoter Array [100718_MM9_Deluxe_Prom_ChIP_HX1]
SUBMITTER: Eric Jonathon Diehl
PROVIDER: GSE61488 | GEO | 2014-09-18
SECONDARY ACCESSION(S): PRJNA261293
REPOSITORIES: GEO
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Chater-Diehl Eric J EJ Laufer Benjamin I BI Castellani Christina A CA Alberry Bonnie L BL Singh Shiva M SM
PloS one 20160502 5
The molecular basis of Fetal Alcohol Spectrum Disorders (FASD) is poorly understood; however, epigenetic and gene expression changes have been implicated. We have developed a mouse model of FASD characterized by learning and memory impairment and persistent gene expression changes. Epigenetic marks may maintain expression changes over a mouse's lifetime, an area few have explored. Here, mice were injected with saline or ethanol on postnatal days four and seven. At 70 days of age gene expression ...[more]