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Epigenetic determinants of self-renewal in glioblastoma [ATAC-seq]

ABSTRACT: We over-expressed an epigenetic regulator in a glioblastoma (GBM) primary culture from an adult patient. These GBM cells have cancer stem cell phenotypes, as they have self-renewal properties and tumor initiation potential when transplanted in immunocompromised mice. ATAC-seq was performed on cells over-expressing the epigenetic regulator and control cells expressing EGFP.

ORGANISM(S): Homo sapiens

PROVIDER: GSE67633 | GEO | 2015/12/08

SECONDARY ACCESSION(S): PRJNA280596

REPOSITORIES: GEO

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