FRT thyroid cells: 2D monolayers vs. 3D follicles

ABSTRACT: Transcriptional profiling of the Fischer Rat Thyroid (FRT) cells comparing polarizing cells grown as a confluent two-dimensional monolayer (2D culture system) with cells grown in matrigel where they acquire a three-dimensional follicular structure (3D culture system).The goal was to identify regulators of 3D epithelial thyroid polarization and follicle formation.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE71259 | GEO | 2016/11/24

SECONDARY ACCESSION(S): PRJNA290724

REPOSITORIES: GEO