Coordination of RNA Polymerase II Pausing and 3’ end processing factor recruitment with alternative polyadenylation

ABSTRACT: Sites of RNA polymerase II (pol II) pausing and processing factor recruitment change depending on which alternative poly(A) site is utilized at the IgM locus. In contrast, the extent of pol II CTD Ser2 phosphorylation did not closely correlate with poly(A) site selection. We conclude that changes in properties of the transcription elongation complex closely correlate with utilization of different poly(A) sites.

ORGANISM(S): Mus musculus

PROVIDER: GSE75301 | GEO | 2015/12/03

SECONDARY ACCESSION(S): PRJNA304953

REPOSITORIES: GEO