Genomics

Dataset Information

82

Widespread downregulation of cardiac mitochondrial and sarcomeric genes in patients with sepsis


ABSTRACT: The mechanism(s) for septic cardiomyopathy in humans is not known. To address this, we performed transcriptional profiling of hearts from patients who died from sepsis, in comparison to non-failing human donor hearts that could not be transplanted for technical reasons. Overall design: 20 sepsis patients, 11 ischemic heart disease (IHD), 9 nonischemic dilated cardiomyopathy (DCM), 11 non-failing donors. The additional de-identified, clinical data for GSM2109161-66, GSM2109168-79 (total 18 samples) is provided in the 'Clinical_metadata.xls' (as a series supplementary file).

INSTRUMENT(S): [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]

SUBMITTER: Scot J Matkovich  

PROVIDER: GSE79962 | GEO | 2016-09-22

SECONDARY ACCESSION(S): PRJNA317505

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
GSE79962_Clinical_metadata.xls.gz Xls
GSE79962_RAW.tar Raw
filelist.txt Txt
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