Genomics

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Expression profiling on lactation day 2 mammary epithelial cells from constitutive miR-150 expressing mice compared to controls.


ABSTRACT: Constitutive expression of miR-150 in mammary epithelium causes severe lactation defects. Mammary epithelial cells (MECs) at lactation day 2 were isolated from four homozygous ROSA26-lox-STOP-lox-miR-150 (Stop-150) mice with WAP-driven Cre (WAP-Cre) and compared to MECs from four WAP-Cre control mice. Statistical analysis of the mRNA changes between the two genotypes identified supression of many lipid and cholesterol synthesis genes due to constitutive expression of miR-150.

ORGANISM(S): Mus musculus

PROVIDER: GSE80666 | GEO | 2016/10/01

SECONDARY ACCESSION(S): PRJNA319627

REPOSITORIES: GEO

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