Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

GNPS - the exhaled breath of humanized mice

ABSTRACT: This is GCxGC MS data from exhaled breath from humanized mice as well as germ-free controls. Raw files in CDF format (Figure S5B, S5C, Figure S6D, Figure 5D of associated publication)

INSTRUMENT(S): SepSolve GCxGC-BenchTOF

ORGANISM(S): C57bl/6 Mice

SUBMITTER: Audrey Odom John Andrew L. Kau

PROVIDER: MSV000098837 | GNPS | Fri Aug 15 10:52:00 BST 2025

REPOSITORIES: GNPS

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

the exhaled breath of "humanized" mice

Project description:This is GCxGC MS data from exhaled breath from humanized mice as well as germ-free controls. Raw files in CDF format (Figure S5B, S5C, Figure S6D, Figure 5D of associated publication)

2025-08-15 | MSV000098837 | MassIVE

Exhaled breath from conventional and conventionalized mice

Project description:This is GCxGC MS data from exhaled breath from conventional and conventionalized mice as well as germ-free controls. Raw files in CDF format (Figure 3A-F, Figure S4A-B from our publication)

2025-07-30 | MSV000098688 | MassIVE

The exhaled breath of monocolonized mice

Project description:This is GCxGC MS raw data from exhaled breath from colonized gnotobiotic mice with one of five common gut commensals including A. muciniphila, B. thetaiotaomicron, Collinsella aerofaciens, E. coli, and Ruminococcus torques and sterile media controls. Raw files in CDF format. (Figures 5B and 6 from associated publication)

2025-07-30 | MSV000098692 | MassIVE

Exhaled breath of mice receiving daily isoprene doses

Project description:mzML files used to generate Figure 2B. Isoprene in the exhaled breath of mice receiving daily isoprene doses for 14 days, and exhaled breath of mice receiving concurrent daily vehicle controls, or in the ambient air alone

2025-07-30 | MSV000098686 | MassIVE

Amydala transcriptome changes in germ-free mice

2015-07-09 | GSE66828 | GEO

Medial prefrontal cortex transcriptome changes in germ-free mice

Project description:We sequenced mRNA from 12 samples extracted from mouse prefrontal cortex tissue to generate the first prefrontal cortex-specific murine transcriptome for germ-free mice (GF), conventionally raised controls (CON) and germ-free mice that have been colonized with normal microbiota from postnatal day 21 (exGF).

2016-01-14 | GSE75816 | GEO

Amydala transcriptome changes in germ-free mice

Project description:We sequenced mRNA from 12 samples extracted from mouse amygdala tissue to generate the first amygdala-specific murine transcriptome for germ-free mice (GF), conventionally raised controls (CON) and germ-free mice that have been colonized with normal microbiota from postnatal day 21 (exGF). Equal amounts of RNA from two to three animals were pooled to yield 4 samples per group (CON, GF, and exGF). Pairwise comparisons for CONvsGF, CONvsexGF, GFvsexGF were performed using DESeq2.

2015-07-09 | E-GEOD-66828 | biostudies-arrayexpress

Single-cell RNA-seq provides insight into the underdeveloped immune system of germ-free mice

Project description:Germ-free mice feature a profoundly underdeveloped immune system. Despite recent studies that emphasize the role of specific bacteria-derived metabolites in immune cell development and differentiation, it remains unclear how the lack of microbiota leads to immune deficiencies. Here, we performed droplet-based single-cell RNA sequencing to analyze the bone marrow and peripheral blood of both germ-free and specific pathogen-free mice, identifying 25 distinct cell types. Our findings suggest that neutrophil apoptosis in germ-free mice may be associated with the absence of niacin dehydrogenase, which is derived primarily from Pseudomonas. In addition, germ-free mice exhibited elevated excretion of 5’-methylthioadenosine, increased ERK activation induced by reactive oxygen species, and cessation of the bone marrow stromal antigen 2 signaling pathway in germ-free mice. The responses of monocytes and CD8+ T cells to interferon β and interferon γ were reduced in germ-free mice, which explains their increased susceptibility to viruses. Together, we identified a regulatory mechanism that connects immunodeficiency with the absence of microbiota in germ-free mice and validated these findings using multiple techniques.

2025-04-25 | GSE295200 | GEO

GNPS 3D Germ Free and Specific Pathogen Free Mice

Project description:A collection of metabolomes from organs of germ free and specific pathogen free mice.

2016-07-20 | MSV000079949 | GNPS

Breath Metabolites from Healthy and Asthmatic Children

Project description:mzML files used to generate Figure 1A-F, Figure S1D-E, Figure 7B, Figure S5A-F. Breath samples collected from healthy and asthmatic children

2024-07-15 | MSV000095340 | MassIVE

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data