Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: Hu Zhou
PROVIDER: PXD036051 | iProX | Sat Aug 13 00:00:00 BST 2022
REPOSITORIES: iProX
Tian Yinping Y Wang Yuqiu Y Yin Hongbo H Luo Yawen Y Wei Fangyu F Zhou Hu H Wen Liuqing L
Angewandte Chemie (International ed. in English) 20221109 49
Core fucosylation, the attachment of α1,6-fucose to the innermost N-acetylglucosamine (GlcNAc) residue of N-glycans, has a strong relationship with tumor growth, invasion, metastasis, prognosis, and immune evasion by regulating many membrane proteins. However, details about the functional mechanism are still largely unknown due to the lack of an effective analytical method to identify cell-surface core-fucosylated glycoproteins, and especially glycosylation sites. Here, we developed a sensitive ...[more]