Extracellular vesicles play a central role in the cerebral deep medullary vein reduction-associated brain atrophy

ABSTRACT: EVs were extracted from the serum of normal and DMV-reduction participants and compared their proteome profiles through a combination of liquid chromatography-tandem mass spectroscopy analysis and Tandem Mass Tag label quantitation analysis. In vitro assays were also conducted to access the impact of EVs on the reduction of vein number and brain atrophy, using serum-derived EVs to treat neurons, astrocytes, endothelial cells, and smooth muscle cells.

ORGANISM(S): Homo Sapiens

SUBMITTER: Wei Ge  

PROVIDER: PXD039873 | iProX | Fri Feb 03 00:00:00 GMT 2023

REPOSITORIES: iProX