Proteomics

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High-fat diet alters retinal lipid composition and gene expression networks in mice


ABSTRACT: To reveal whether a long-term HFD alters gene expression levels in the retina, we used 4D-label free mass spectrometry to quantify proteins in the whole retinas of HFM and age-mated NM. As the liver plays a crucial role in metabolism of the whole body, HFD has a huge impact on gene expression in the liver. To compare the similarities and differences in the effects of a HFD on retinal and hepatic gene regulatory networks, we also performed proteomic analyses on the livers from HFM and NM.

ORGANISM(S): Mus Musculus

SUBMITTER: Lin Zhang  

PROVIDER: PXD052242 | iProX | Tue May 14 00:00:00 BST 2024

REPOSITORIES: iProX

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