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Comparison of the significantly differentially expressed protein between K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB treated with 8% xylose

ABSTRACT: The K. pneumoniae K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB isolates were cultured overnight in MRS medium, then 1:200 diluted in MRS medium with 8% xylose to reach the exponential growth phase. The control group was K2044 treated with 8% xylose. The experiment was performed in triplicate.

ORGANISM(S): Klebsiella Pneumoniae 1191100241

SUBMITTER: Zewen Wen

PROVIDER: PXD057506 | iProX | Mon Nov 04 00:00:00 GMT 2024

REPOSITORIES: iProX

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Klebsiella pneumoniae under xylose pressure: the growth adaptation, antimicrobial susceptibility, global proteomics analysis and role of XylA and XylB proteins.

Yi Ruolan R Zheng Jiaoyang J Xu Zhichao Z Wu Jiayan J Liu Fangfang F Zheng Jinxin J Li Duoyun D Han Shiqing S Yu Zhijian Z

BMC microbiology 20250429 1

Klebsiella pneumoniae can be cultured in medium with xylose as the sole carbon source. However, the effect of xylose exposure on its growth adaptation, virulence, antimicrobial susceptibility, and proteomic response remain unclear. Here, we show that low concentrations of xylose (≤ 2%) promote the planktonic growth of three K. pneumoniae isolates (K2044, EKP19, and EKP108) in a concentration-dependent manner, while 8% xylose consistently inhibits their planktonic growth. Notably, the xylose-indu ...[more]

PMID: 40301709

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