Proteomic analysis of human circulating neutrophils upon multi states
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Wei Yan
PROVIDER: PXD059138 | iProX | Mon Dec 23 00:00:00 GMT 2024
REPOSITORIES: iProX
Publications
Proteomic portrait of degranulation program in human circulating neutrophils upon multi-inflammatory and infectious activation.
Hua Ying Y Zhou Ziqi Z Zhang Can C Fang Hai H Wu Mingxing M Chen Zhiyong Z Ku Xin X Yan Wei W
Molecular & cellular proteomics : MCP 20250929
Neutrophils respond rapidly to inflammation and infection via defense mechanisms, including degranulation, reactive oxygen species (ROS) production, and neutrophil extracellular trap (NET) formation (known as 'NETosis'). As the most abundant neutrophil components, granule proteins constitute the major mediators of neutrophil effector functions and likely orchestrate their functional diversity. However, a systematic profile of these proteins, particularly their temporal release dynamics during in ...[more]
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