Proteomics

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Preservation of collagen in the soft tissue of frozen mammoths

ABSTRACT: To evaluate whether collagen is preserved in the soft tissues of frozen mammoths for 40,000 years, we performed protein identification of mammoth lung and kidney (and elephant bone and kidney as controls) after trypsin digestion.

ORGANISM(S): Mammuthus Primigenius Elephas Maximus Indicus

SUBMITTER: Shunji Hattori 

PROVIDER: PXD024006 | JPOST Repository | Tue Oct 05 00:00:00 BST 2021

REPOSITORIES: jPOST

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We investigated the characteristics of extracellular matrix (ECM) in the soft tissue of two frozen baby woolly mammoths (Mammuthus primigenius) that died and were buried in Siberian permafrost approximately 40,000 years ago. Morphological and biochemical analyses of mammoth lung and liver demonstrated that those soft tissues were preserved at the gross anatomical and histological levels. The ultrastructure of ECM components, namely a fibrillar structure with a collagen-characteristic pattern of  ...[more]