Proteomics

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Blast wave effect on brain proteome (rat hippocampus)


ABSTRACT: These data show differences in up- and down-regulation for protein abundances in the hippocampus of double blast vs. sham rats. Tandem mass tags (TMT)-MS results showed 136 up-regulated and 94 down-regulated proteins between the two groups. These TMT-MS findings revealed changes never described before in blast studies. In the absence of behavioral changes, these proteomic data further support the existence of an asymptomatic blast-induced molecular altered status (ABIMAS) associated with specific protein changes in the rat hippocampus.

INSTRUMENT(S): 1200 series LC/MSD SL

ORGANISM(S): Rattus (ncbitaxon:10114)

SUBMITTER: Diego Iacono  

PROVIDER: MSV000092956 | MassIVE |

REPOSITORIES: MassIVE

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