Integrated Phosphoproteomics of Theileria annulata-Infected Cells: Unveiling Host and Parasite Kinase Networks and Signaling Pathways
Ontology highlight
ABSTRACT: This study employs comparative phosphoproteomics to investigate the changes in protein phosphorylation (post-translational modifications) induced by Theileria annulata infection in host cells. Three groups are analyzed: bovine lymphocytes infected with T. annulata, uninfected control lymphocytes, and lymphocytes treated with buparvaquone, a drug that clears the parasite. The analysis aims to identify and compare the kinase networks and signaling pathways activated in both the host and the parasite during infection.
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Theileria Annulata (ncbitaxon:5874)
SUBMITTER:
Dr. Paresh Sharma
PROVIDER: MSV000094978 | MassIVE | Mon Jun 10 23:45:00 BST 2024
REPOSITORIES: MassIVE
ACCESS DATA