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Combination of proximity biotinylation proteomics and optogenetics unveils key proteins promoting Pathological structural conversion of a-synuclein

ABSTRACT: This submission contains the mass spectrometry files for the manuscript by Maxime Teixeira et al. that describes the establishment and deployment of an optogenetics approach combined with proximity biotionylation to characterize the formation of a-synuclein aggregates in cellulo. Proximity biotinylation experiments were performed from Flp-In T-REx HEK293 cells and MS files were acquired on an Orbitrap Fusion mass spectrometer. For questions, please contact Jean-Philippe Lambert (Jean-Philippe.Lambert@crchudequebec.ulaval.ca).

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Jean-Philippe Lambert

PROVIDER: MSV000095182 | MassIVE | Fri Jun 28 12:36:00 BST 2024

SECONDARY ACCESSION(S): PXD053499

REPOSITORIES: MassIVE

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Combination of proximity biotinylation proteomics and optogenetics unveils key proteins promoting Pathological structural conversion of a-synuclein

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