Proteomics

Dataset Information

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Breath Metabolites from Healthy and Asthmatic Children


ABSTRACT: mzML files used to generate Figure 1 A-F, Figure S1 D-E, Figure 6 B, Figure S5 D-F. Breath samples collected from healthy and asthmatic children

INSTRUMENT(S): Agilent GC-qTOF

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Audrey Odom John   Andrew L. Kau  

PROVIDER: MSV000095340 | MassIVE | Mon Jul 15 13:41:00 BST 2024

REPOSITORIES: MassIVE

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Publications


The gut microbiota is crucial to health, yet implementation of microbiota-based therapeutics is limited by the lack of rapid diagnostics. We hypothesize that breath contains gut microbe-derived volatile organic compounds (VOCs) reflecting microbiota composition and metabolism. In healthy children, we found that breath VOC composition (or volatilome), assessed by gas chromatography-mass spectrometry, correlates with gut microbiome composition and function. By capturing exhaled breath from human-s  ...[more]

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