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CoIP proteome of KERP2-related Entamoeba histolytica transformants

ABSTRACT: Entamoeba histolytica, the protozoan parasite responsible for amoebiasis, employs a diverse arsenal of virulence factors to facilitate infection and evade host immune responses. In this study, we identify KERP2 as a dual-function effector involved in both parasite homeostasis and host cell modulation. To investigate its subcellular interactions, E. histolytica trophozoites expressing HA-tagged full-length KERP2 or the truncated variant HA-KERP2(1-184) were fractionated into nuclear and cytosolic components, followed by co-immunoprecipitation analysis.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Entamoeba Histolytica Hm-1:imss (ncbitaxon:294381)

SUBMITTER: Ruofan Peng

PROVIDER: MSV000097502 | MassIVE | Thu Apr 03 01:44:00 BST 2025

SECONDARY ACCESSION(S): PXD062553

REPOSITORIES: MassIVE

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